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Journal article

The effect of chronic cytomegalovirus infection on pneumococcal vaccine responses.

Abstract:

BACKGROUND: Immune function declines with age and has been associated with reduced vaccine responsiveness. Chronic infection with cytomegalovirus (CMV) has been proposed as a contributor to poorer responses in older adults. A pneumococcal vaccine has been recommended in the United Kingdom for those aged >65 years since 2003 to prevent pneumococcal disease. METHODS: We evaluated the effect of age and CMV status on pneumococcal vaccine responses in 348 individuals aged 50-70 years. RESULTS: ...

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Publication status:
Published

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Publisher copy:
10.1093/infdis/jit673

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Institution:
University of Oxford
Department:
Oxford, MSD, Primary Care Health Sciences
Role:
Author
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Publisher:
University of Chicago Press
Journal:
The Journal of infectious diseases
Volume:
209
Issue:
10
Pages:
1635-1641
Publication date:
2014-05-05
DOI:
EISSN:
1537-6613
ISSN:
0022-1899
URN:
uuid:885f85f1-af12-4af9-8ae6-5d2fa42d3424
Source identifiers:
441664
Local pid:
pubs:441664

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