- Abstract:
-
BACKGROUND: Immune function declines with age and has been associated with reduced vaccine responsiveness. Chronic infection with cytomegalovirus (CMV) has been proposed as a contributor to poorer responses in older adults. A pneumococcal vaccine has been recommended in the United Kingdom for those aged >65 years since 2003 to prevent pneumococcal disease. METHODS: We evaluated the effect of age and CMV status on pneumococcal vaccine responses in 348 individuals aged 50-70 years. RESULTS: ...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1093/infdis/jit673
-
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- Publisher:
- University of Chicago Press
- Journal:
- The Journal of infectious diseases
- Volume:
- 209
- Issue:
- 10
- Pages:
- 1635-1641
- Publication date:
- 2014-05-05
- DOI:
- EISSN:
-
1537-6613
- ISSN:
-
0022-1899
- URN:
-
uuid:885f85f1-af12-4af9-8ae6-5d2fa42d3424
- Source identifiers:
-
441664
- Local pid:
- pubs:441664
- Language:
- English
- Keywords:
- Copyright date:
- 2014
Journal article
The effect of chronic cytomegalovirus infection on pneumococcal vaccine responses.
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