Back to Search

Journal article

RFX6 Regulates Insulin Secretion by Modulating Ca2+ Homeostasis in Human β Cells

Abstract:: Development and function of pancreatic β cells involve the regulated activity of specific transcription factors. RFX6 is a transcription factor essential for mouse β cell differentiation that is mutated in monogenic forms of neonatal diabetes. However, the expression and functional roles of RFX6 in human β cells, especially in pathophysiological conditions, are poorly explored. We demonstrate the presence of RFX6 in adult human pancreatic endocrine cells. Using the recently developed human β ...
Expand abstract
Collapse abstract

Actions

Email

Email this record

Send the bibliographic details of this record to your email address.

Your Email
Please enter the email address that the record information will be sent to.

-
Your message (optional)
Please add any additional information to be included within the email.
Cite

Cite this record

APA Style

Chandra, V., Albagli-Curiel, O., Hastoy, B., Piccand, J., Randriamampita, C., Vaillant, E., Cavé, H., Busiah, K., Froguel, P., Vaxillaire, M., Rorsman, P., Polak, M., & Scharfmann, R. (2014). RFX6 Regulates Insulin Secretion by Modulating Ca2+ Homeostasis in Human β Cells. Cell Reports, 9(6), 2206–2218.

MLA Style

Chandra, V., et al. “RFX6 Regulates Insulin Secretion by Modulating Ca2+ Homeostasis in Human β Cells.” Cell Reports, vol. 9, no. 6, Elsevier, 2014, pp. 2206–18.

Chicago Style

Chandra, V, O Albagli-Curiel, B Hastoy, J Piccand, C Randriamampita, E Vaillant, H Cavé, et al. 2014. “RFX6 Regulates Insulin Secretion by Modulating Ca2+ Homeostasis in Human β Cells.” Cell Reports 9 (6): 2206–18.
Tweet
Print

Access Document

Publisher copy:: 10.1016/j.celrep.2014.11.010

Authors

+ Chandra, V More by this author

Role:

Author

+ Albagli-Curiel, O More by this author

Role:

Author

+ Hastoy, B More by this author

Role:

Author

+ Piccand, J More by this author

Role:

Author

+ Randriamampita, C More by this author

Role:

Author

More authors...

Bibliographic Details

Publisher:: Elsevier
Journal:: Cell Reports
Volume:: 9
Issue:: 6
Pages:: 2206-2218
Publication date:: 2014-12-24
DOI:: 10.1016/j.celrep.2014.11.010
EISSN:: 2211-1247

Item Description

Language:: English
Pubs id:: pubs:502688
UUID:: uuid:885aa6df-636a-4471-824e-ee32eb5e902d
Local pid:: pubs:502688
Source identifiers:: 502688
Deposit date:: 2015-01-15

Terms of use

Copyright date:: 2014

Licence:: Terms and Conditions of Use for Oxford University Research Archive

Metrics

Views and Downloads

About views and downloads

If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP