- Abstract:
-
We tested the abilities of two potent non-N-methyl-D-aspartate (non-NMDA) glutamate antagonists [2,3-dihydroxy-6-nitro-7-sulfamoylbenzo(F)quinoxaline (NBQX)] and [1-(4-aminophenyl)-4-methyl-7,8-methylene-dioxy-5H-2,3-benzodiazep ine hydrochloride (GYKI 52466)] to reduce neocortical infarction following 2 h of transient middle cerebral artery occlusion in a hypertensive stroke model in the rat and compared these effects against, and in combination with, a potent NMDA antagonist [(+)-5-methyl-1...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1038/jcbfm.1994.32
-
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- Journal:
- Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
- Volume:
- 14
- Issue:
- 2
- Pages:
- 251-261
- Publication date:
- 1994-03-05
- DOI:
- EISSN:
-
1559-7016
- ISSN:
-
0271-678X
- URN:
-
uuid:88570ed8-d1cd-40f7-bc47-e20cddaa5b3a
- Source identifiers:
-
80177
- Local pid:
- pubs:80177
- Language:
- English
- Keywords:
- Copyright date:
- 1994
Journal article
Delayed treatment with AMPA, but not NMDA, antagonists reduces neocortical infarction.
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