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Journal article

The negative transcriptional regulator NmrA discriminates between oxidized and reduced dinucleotides.

Abstract:: NmrA, a transcription repressor involved in the regulation of nitrogen metabolism in Aspergillus nidulans,is a member of the short-chain dehydrogenase reductase superfamily. Isothermal titration calorimetry and differential scanning calorimetry have been used to show NmrA binds NAD+ and NADP+ with similar affinity (average KD 65 microM) but has a greatly reduced affinity for NADH and NADPH (average KD 6.0 mM). The structure of NmrA in a complex with NADP+ reveals how repositioning a His-37 si...
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Publication status:: Published

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APA Style

Lamb, H., Leslie, K., Dodds, A., Nutley, M., Cooper, A., Johnson, C., Thompson, P., Stammers, D., & Hawkins, A. (2003). The negative transcriptional regulator NmrA discriminates between oxidized and reduced dinucleotides. Journal of Biological Chemistry, 278(34), 32107–32114.

MLA Style

Lamb, H., et al. “The Negative Transcriptional Regulator NmrA Discriminates between Oxidized and Reduced Dinucleotides.” Journal of Biological Chemistry, vol. 278, no. 34, 2003, pp. 32107–14.

Chicago Style

Lamb, H, K Leslie, A Dodds, M Nutley, A Cooper, C Johnson, P Thompson, D Stammers, and A Hawkins. 2003. “The Negative Transcriptional Regulator NmrA Discriminates between Oxidized and Reduced Dinucleotides.” Journal of Biological Chemistry 278 (34): 32107–14.
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Publisher copy:: 10.1074/jbc.M304104200

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+ Lamb, H More by this author

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+ Leslie, K More by this author

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+ Dodds, A More by this author

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+ Nutley, M More by this author

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+ Cooper, A More by this author

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Bibliographic Details

Journal:: Journal of biological chemistry
Volume:: 278
Issue:: 34
Pages:: 32107-32114
Publication date:: 2003-08-01
DOI:: 10.1074/jbc.M304104200
EISSN:: 1083-351X
ISSN:: 0021-9258

Item Description

Language:: English
Keywords:: DNA Primers

Fungal Proteins

Calorimetry, Differential Scanning

Models, Molecular

Aspergillus nidulans

Oxidation-Reduction

Repressor Proteins

Base Sequence
Pubs id:: pubs:72613
UUID:: uuid:883dcf17-13a6-41a3-91d3-833df6971a11
Local pid:: pubs:72613
Source identifiers:: 72613
Deposit date:: 2012-12-19

Terms of use

Copyright date:: 2003

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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