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Cerebrospinal fluid levels of markers of brain parenchymal damage in Vietnamese adults with severe malaria.

Abstract:

A retrospective study of cerebrospinal fluid (CSF) markers of brain parenchymal damage was conducted in Vietnamese adults with severe malaria. Three markers were analysed by immunoassays: the microtubule-associated protein tau, for degenerated axons; neuron-specific enolase (NSE), for neurons; and S100B for astrocytes. The mean concentration of tau proteins in the CSF was significantly raised in patients with severe malaria compared with controls (P=0.0003) as reported for other central nervo...

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Publication status:
Published

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Authors


Medana, IM More by this author
Lindert, RB More by this author
Wurster, U More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Tropical Medicine
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Thailand/Laos MOP
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Journal:
Transactions of the Royal Society of Tropical Medicine and Hygiene
Volume:
99
Issue:
8
Pages:
610-617
Publication date:
2005-08-05
DOI:
EISSN:
1878-3503
ISSN:
0035-9203
URN:
uuid:883bcb87-60c8-424b-a1ee-6867e4f142cb
Source identifiers:
12924
Local pid:
pubs:12924

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