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Journal article

Immunogenicity and reactogenicity of novel adenovirus type 26 and modified vaccinia Ankara-vectored Ebola vaccines: A randomized clinical trial

Abstract:

Importance

Developing effective vaccines against Ebola virus is a global priority.

Objective

To evaluate an adenovirus-type 26 vector vaccine encoding Ebola glycoprotein (Ad26.ZEBOV) and a modified vaccinia Ankara vector vaccine, encoding glycoproteins from Ebola virus, Sudan virus, Marburg virus and Tai Forest virus nucleoprotein (MVA-BN-Filo).

Design, Setting and Participants

Single-center, randomized, placebo-controlled, observer-blind, phase I t...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1001/jama.2016.4218

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Paediatrics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Paediatrics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Paediatrics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Paediatrics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Paediatrics
Role:
Author
Crucell Holland B.V More from this funder
Publisher:
American Medical Association Publisher's website
Journal:
Journal of the American Medical Association Journal website
Volume:
315
Issue:
15
Pages:
1610-1623
Publication date:
2016-04-19
Acceptance date:
2016-03-24
DOI:
ISSN:
0002-9955
Pubs id:
pubs:611644
UUID:
uuid:88372212-f538-476c-808e-fef844ce1234
Local pid:
pubs:611644
Source identifiers:
611644
Deposit date:
2016-03-24

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