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Molecular therapeutic targets in rheumatoid arthritis.

Abstract:

In an attempt to combat the pain and damage generated by rheumatoid arthritis (ra), new drugs are being developed to target molecular aspects of the disease process. Recently, a major development has been the use of biologicals (antibodies and soluble receptors) that neutralise the activity of tumour necrosis factor alpha (TNF-alpha) and interleukin 1 (IL-1), both of which are involved in disease progression. An increase in our understanding of cell and molecular biology has resulted in the i...

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Publisher copy:
10.1017/S1462399405009488

Authors


Andreakos, E More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Foxwell, BM More by this author
Journal:
Expert reviews in molecular medicine
Volume:
7
Issue:
16
Pages:
1-20
Publication date:
2005-08-05
DOI:
EISSN:
1462-3994
ISSN:
1462-3994
URN:
uuid:88256e31-88fc-4c86-a012-fa583ed5cb47
Source identifiers:
223920
Local pid:
pubs:223920

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