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Corneal epithelial wound healing

Abstract:

We propose a reaction-diffusion model of the mechanisms involved in the healing of corneal surface wounds. The model focuses on the stimulus for increased mitotic and migratory activity, specifically the role of epidermal growth factor. We determine an analytic approximation for the speed of travelling wave solutions of the model in terms of the parameters and verify the results numerically. By comparing the predicted speed with experimentally measured healing rates, we conclude that serum-de...

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Publication date:
1995-01-01
URN:
uuid:8810906e-33f3-47f3-ae43-439dfcf211d1
Local pid:
oai:eprints.maths.ox.ac.uk:558

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