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Medial temporal lobe activity at recognition increases with the duration of mnemonic delay during an object working memory task.

Abstract:

Object working memory (WM) engages a disseminated neural network, although the extent to which the length of time that data is held in WM influences regional activity within this network is unclear. We used functional magnetic resonance imaging to study a delayed matching to sample task in 14 healthy subjects, manipulating the duration of mnemonic delay. Across all lengths of delay, successful recognition was associated with the bilateral engagement of the inferior and middle frontal gyri and...

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Publisher copy:
10.1002/hbm.20357

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Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
Role:
Author
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Journal:
Human brain mapping
Volume:
28
Issue:
11
Pages:
1235-1250
Publication date:
2007-11-05
DOI:
EISSN:
1097-0193
ISSN:
1065-9471
URN:
uuid:88089291-d931-4f1d-8b10-db7ab813fcf1
Source identifiers:
403457
Local pid:
pubs:403457

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