Functional Changes in the Language Network in Response to Increased Amyloid β Deposition in Cognitively Intact Older Adults.
Word finding symptoms are frequent early in the course of Alzheimer's disease and relate principally to functional changes in left posterior temporal cortex. In cognitively intact older adults, we examined whether amyloid load affects the network for language and associative-semantic processing. Fifty-six community-recruited subjects (52-74 years), stratified for apolipoprotein E and brain-derived neurotrophic factor genotype, received a neurolinguistic assessment, (18)F-flutemetamol positron...Expand abstract
- Publisher copy:
- Copyright date:
If you are the owner of this record, you can report an update to it here: Report update to this record