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Journal article

Whole-genome linkage analysis of rheumatoid arthritis susceptibility loci in 252 affected sibling pairs in the United Kingdom.

Abstract:

OBJECTIVE: To undertake a systematic whole-genome screen to identify regions exhibiting genetic linkage to rheumatoid arthritis (RA). METHODS: Two hundred fifty-two RA-affected sibling pairs from 182 UK families were genotyped using 365 highly informative microsatellite markers. Microsatellite genotyping was performed using fluorescent polymerase chain reaction primers and semiautomated DNA sequencing technology. Linkage analysis was undertaken using MAPMAKER/SIBS for single-point and multip...

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Publication status:
Published

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Publisher copy:
10.1002/art.10147

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Journal:
Arthritis and rheumatism
Volume:
46
Issue:
3
Pages:
632-639
Publication date:
2002-03-01
DOI:
EISSN:
1529-0131
ISSN:
0004-3591
Source identifiers:
108429
Language:
English
Keywords:
Pubs id:
pubs:108429
UUID:
uuid:88005d5b-9885-41af-81ca-338f3064a4ab
Local pid:
pubs:108429
Deposit date:
2012-12-19

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