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Journal article

Synovial cellular and molecular signatures stratify clinical response to csDMARD therapy and predict radiographic progression in early rheumatoid arthritis patients

Abstract:
Objectives To unravel the hierarchy of cellular/molecular pathways in the disease tissue of early, treatment-naïve rheumatoid arthritis (RA) patients and determine their relationship with clinical phenotypes and treatment response/outcomes longitudinally.

Methods 144 consecutive treatment-naïve early RA patients (<12 months symptoms duration) underwent ultrasound-guided synovial biopsy before and 6 months after disease-modifying antirheumatic dr... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

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Publisher copy:
10.1136/annrheumdis-2018-214539

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Publisher:
BMJ Publishing Group Publisher's website
Journal:
Annals of the Rheumatic Diseases Journal website
Volume:
78
Issue:
6
Publication date:
2019-03-16
Acceptance date:
2019-02-14
DOI:
EISSN:
1468-2060
ISSN:
0003-4967
Pubs id:
pubs:973749
URN:
uri:87d7d6d6-049f-4d30-bb8b-2b4496c476a2
UUID:
uuid:87d7d6d6-049f-4d30-bb8b-2b4496c476a2
Local pid:
pubs:973749

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