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Journal article

CD8(+) T cells mediate CD40-independent maturation of dendritic cells in vivo.

Abstract:

Induction of cytotoxic T lymphocyte (CTL) responses against minor histocompatibility antigens is dependent upon the presence of T cell help and requires the interaction of CD40 on dendritic cells (DCs) with CD40 ligand on activated T helper cells (Th). This study demonstrates that CD40 is neither involved in Th-dependent nor Th-independent antiviral CTL responses. Moreover, the data show that DC maturation occurs in vivo after viral infection in the absence of CD40 and Th. This maturation did...

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Publication status:
Published

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Publisher copy:
10.1084/jem.189.12.1875

Authors


Journal:
The Journal of experimental medicine
Volume:
189
Issue:
12
Pages:
1875-1884
Publication date:
1999-06-05
DOI:
EISSN:
1540-9538
ISSN:
0022-1007
URN:
uuid:87cf96cf-ee73-4dbe-9503-f5807b24aa3d
Source identifiers:
469230
Local pid:
pubs:469230

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