Journal article
CD45RA distinguishes CD4+CD25+CD127−/low TSDR demethylated regulatory T cell subpopulations with differential stability and susceptibility to tacrolimus-mediated inhibition of suppression
- Abstract:
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Background: Adoptive transfer of forkhead box protein (FOX)3+ regulatory T (Treg) cells offers a promising strategy to reduce damage to an allograft by the recipient's immune system. Identification of cell surface markers sufficient to purify Treg cells expanded ex vivo to remove cellular contaminants requires optimization. Furthermore, the expanded Treg must be able to survive, expand, and suppress in allograft recipients exposed to immunosuppressants,...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
-
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(Version of record, pdf, 833.9KB)
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- Publisher copy:
- 10.1097/TP.0000000000001278
Authors
Bibliographic Details
- Publisher:
- Lippincott, Williams & Wilkins Publisher's website
- Journal:
- Transplantation Journal website
- Volume:
- 101
- Issue:
- 2
- Pages:
- 302–309
- Publication date:
- 2017-02-01
- Acceptance date:
- 2016-03-25
- DOI:
- EISSN:
-
1534-6080
- ISSN:
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0041-1337
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:675082
- UUID:
-
uuid:87c77222-7826-4cd8-9271-1134a5865e7d
- Local pid:
- pubs:675082
- Source identifiers:
-
675082
- Deposit date:
- 2017-03-09
Terms of use
- Copyright holder:
- Wolters Kluwer Health
- Copyright date:
- 2017
- Notes:
- © 2017 Wolters Kluwer Health, Inc. All rights reserved. This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
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