Journal article
Regulation of major histocompatibility complex class II gene expression, genetic variation and disease.
- Abstract:
-
Major histocompatibility complex (MHC) class II molecules are central to adaptive immune responses and maintenance of self-tolerance. Since the early 1970s, the MHC class II region at chromosome 6p21 has been shown to be associated with a remarkable number of autoimmune, inflammatory and infectious diseases. Given that a full explanation for most MHC class II disease associations has not been reached through analysis of structural variation alone, in this review we examine the role of genetic...
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- Publication status:
- Published
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- Publisher copy:
- 10.1038/gene.2009.83
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Bibliographic Details
- Journal:
- Genes and immunity
- Volume:
- 11
- Issue:
- 2
- Pages:
- 99-112
- Publication date:
- 2010-03-01
- DOI:
- EISSN:
-
1476-5470
- ISSN:
-
1466-4879
- Source identifiers:
-
7919
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:7919
- UUID:
-
uuid:87b7c09e-0d1c-40ed-99b5-0f609a6935d7
- Local pid:
- pubs:7919
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2010
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