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Analysis of T cell receptor V alpha polymorphisms in rheumatoid arthritis.

Abstract:

OBJECTIVE: To test for association of T cell receptor (TCR) V alpha polymorphisms and rheumatoid arthritis (RA) in British and Swiss white populations. METHODS: TCRAV polymorphisms were analysed in RA patients and controls by single strand conformational polymorphism (SSCP) analysis. Associations were sought between defined genotypes and RA, and the effect of HLA-DR4 status analysed. Putative associations were then retested further in new groups of patients and controls. Overall, 360 RA patie...

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Publication status:
Published

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Publisher copy:
10.1136/ard.57.1.49

Authors


Ibberson, M More by this author
Péclat, V More by this author
Guerne, PA More by this author
Tiercy, JM More by this author
Wordsworth, P More by this author
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Journal:
Annals of the rheumatic diseases
Volume:
57
Issue:
1
Pages:
49-51
Publication date:
1998-01-05
DOI:
EISSN:
1468-2060
ISSN:
0003-4967
URN:
uuid:879c7301-4c04-4954-851e-13cc11b989b7
Source identifiers:
108801
Local pid:
pubs:108801

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