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Journal article

Conservation of the Duchenne muscular dystrophy gene in mice and humans.

Abstract:

A portion of the Duchenne muscular dystrophy (DMD) gene transcript from human fetal skeletal muscle and mouse adult heart was sequenced, representing approximately 25 percent of the total, 14-kb DMD transcript. The nucleic acid and predicted amino acid sequences from the two species are nearly 90 percent homologous. The amino acid sequence that is predicted from this portion of the DMD gene indicates that the protein product might serve a structural role in muscle, but the abundance and tissu...

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Publication status:
Published

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Publisher copy:
10.1126/science.3659917

Authors


Hoffman, EP More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, WTC Human Genetics
Feener, CC More by this author
Kunkel, LM More by this author
Journal:
Science (New York, N.Y.)
Volume:
238
Issue:
4825
Pages:
347-350
Publication date:
1987-10-05
DOI:
EISSN:
1095-9203
ISSN:
0036-8075
URN:
uuid:8799f3ce-702f-4b23-9545-79c2fb017a16
Source identifiers:
115647
Local pid:
pubs:115647

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