Cell-to-cell HIV-1 spread and its implications for immune evasion.
PURPOSE OF REVIEW: The ability of HIV-1 to move between cells via direct cell-cell transmission is currently receiving a lot of attention. This review will discuss cell-cell spread of HIV-1 in terms of cellular and molecular mechanisms and will consider the evidence for immune and therapeutic evasion. RECENT FINDINGS: Recent studies relating to the cell biology of HIV-1 cell-cell spread have sparked considerable renewed interest in the field. However, questions are being raised concerning bo...Expand abstract
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