Progressive genome-wide introgression in agricultural Campylobacter coli.

Journal article

Hybridization between distantly related organisms can facilitate rapid adaptation to novel environments, but is potentially constrained by epistatic fitness interactions among cell components. The zoonotic pathogens Campylobacter coli and C. jejuni differ from each other by around 15% at the nucleotide level, corresponding to an average of nearly 40 amino acids per protein-coding gene. Using whole genome sequencing, we show that a single C. coli lineage, which has successfully colonized an ag...

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Authors: Sheppard, S; Didelot, X; Jolley, K; Darling, A; Pascoe, B

• Publication status: Published
• Journal: Molecular ecology
• Volume: 22
• Issue: 4
• Pages: 1051-1064
• Publication date: 2013-02-01
• DOI: 10.1111/mec.12162
• EISSN: 1365-294X
• ISSN: 0962-1083
• Language: English
• Keywords: Sequence Analysis, DNA; Genome, Bacterial; Models, Genetic; Campylobacter jejuni; DNA, Bacterial; Campylobacter coli; Hybridization, Genetic; Evolution, Molecular; Likelihood Functions