- Abstract:
-
BACKGROUND/AIMS: Ursodeoxycholic acid (UDCA) has been shown to improve serum liver tests in primary sclerosing cholangitis (PSC), but controlled trials have shown inconsistent effects on liver histology, and did not reveal a survival benefit. This pilot, randomised dose-ranging trial attempted to determine whether further enrichment of the bile acid pool with UDCA would lead to an improvement in outcome for PSC patients. METHODS: Thirty-one patients with PSC were randomised to treatment with...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1016/j.jhep.2007.12.023
-
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- Journal:
- Journal of hepatology
- Volume:
- 48
- Issue:
- 5
- Pages:
- 792-800
- Publication date:
- 2008-05-05
- DOI:
- EISSN:
-
1600-0641
- ISSN:
-
0168-8278
- URN:
-
uuid:877eafd6-936d-469b-aba1-943c4979722b
- Source identifiers:
-
112850
- Local pid:
- pubs:112850
- Language:
- English
- Keywords:
- Copyright date:
- 2008
Journal article
High dose ursodeoxycholic acid for the treatment of primary sclerosing cholangitis is safe and effective.
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