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Journal article

High dose ursodeoxycholic acid for the treatment of primary sclerosing cholangitis is safe and effective.

Abstract:

BACKGROUND/AIMS: Ursodeoxycholic acid (UDCA) has been shown to improve serum liver tests in primary sclerosing cholangitis (PSC), but controlled trials have shown inconsistent effects on liver histology, and did not reveal a survival benefit. This pilot, randomised dose-ranging trial attempted to determine whether further enrichment of the bile acid pool with UDCA would lead to an improvement in outcome for PSC patients. METHODS: Thirty-one patients with PSC were randomised to treatment with...

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Publication status:
Published

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Publisher copy:
10.1016/j.jhep.2007.12.023

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Journal:
Journal of hepatology
Volume:
48
Issue:
5
Pages:
792-800
Publication date:
2008-05-05
DOI:
EISSN:
1600-0641
ISSN:
0168-8278
URN:
uuid:877eafd6-936d-469b-aba1-943c4979722b
Source identifiers:
112850
Local pid:
pubs:112850

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