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Journal article

Decontamination strategies and bloodstream infections with antibiotic-resistant microorganisms in ventilated patients: a randomized clinical trial

Abstract:

Importance: The effects of chlorhexidine (CHX) mouthwash, selective oropharyngeal decontamination (SOD), and selective digestive tract decontamination (SDD) on patient outcomes in ICUs with moderate to high levels of antibiotic resistance are unknown.

Objective: To determine associations between CHX 2%, SOD, and SDD and the occurrence of ICU-acquired bloodstream infections with multidrug-resistant gram-negative bacteria (MDRGNB) and 28-day mortality in ICUs with moderate to high ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1001/jama.2018.13765

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
ORCID:
0000-0002-9445-7217
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Publisher:
American Medical Association Publisher's website
Journal:
Journal of the American Medical Association Journal website
Volume:
320
Issue:
20
Pages:
2087-2098
Publication date:
2018-10-22
Acceptance date:
2018-10-05
DOI:
EISSN:
1538-3598
ISSN:
0098-7484
Source identifiers:
934785
Pubs id:
pubs:934785
UUID:
uuid:877e79d8-4451-4a93-bf0e-77be05c9de83
Local pid:
pubs:934785
Deposit date:
2018-10-26

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