Journal article icon

Journal article

Persistence and resistance as complementary bacterial adaptations to antibiotics

Abstract:

Bacterial persistence represents a simple of phenotypic heterogeneity, whereby a proportion of cells in an isogenic bacterial population can survive exposure to lethal stresses such as antibiotics. In contrast, genetically based antibiotic resistance allows for continued growth in the presence of antibiotics. It is unclear, however, whether resistance and persistence are complementary or alternative evolutionary adaptations to antibiotics. Here, we investigate the co-evolution of resistance a...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1111/jeb.12864

Authors


More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Zoology
Role:
Author
Publisher:
Wiley Publisher's website
Journal:
Journal of evolutionary biology Journal website
Volume:
29
Issue:
6
Pages:
1223-1233
Publication date:
2016-04-06
Acceptance date:
2016-03-09
DOI:
EISSN:
1420-9101
ISSN:
1010-061X
Source identifiers:
611795
Language:
English
Keywords:
Pubs id:
pubs:611795
UUID:
uuid:8765ecd5-7acf-4cf6-959f-b54f6425f59f
Local pid:
pubs:611795
Deposit date:
2016-06-27

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP