Journal article
Stabilization of influenza virus replication intermediates is dependent on the RNA-binding but not the homo-oligomerization activity of the viral nucleoprotein.
- Abstract:
-
The influenza virus nucleoprotein (NP) is believed to play a central role in directing a switch from RNA genome transcription to replication by the viral RNA polymerase. However, this role has recently been disputed with the proposal of alternative regulatory mechanisms. It has been suggested that the expression of viral polymerase and NP allows genome replication by stabilization of cRNA replication intermediates and complementary ribonucleoprotein (cRNP) assembly. Here, we demonstrate that ...
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- Publication status:
- Published
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- Publisher copy:
- 10.1128/jvi.00695-11
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Authors
Bibliographic Details
- Journal:
- Journal of virology
- Volume:
- 85
- Issue:
- 22
- Pages:
- 12073-12078
- Publication date:
- 2011-11-01
- DOI:
- EISSN:
-
1098-5514
- ISSN:
-
0022-538X
- Source identifiers:
-
175232
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:175232
- UUID:
-
uuid:8758606c-b867-456e-81e2-f10be791ff53
- Local pid:
- pubs:175232
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2011
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