Global HIV-1 diversity surveillance.

Journal article

The global distribution of HIV-1 subtypes and recombinants is extremely complex and dynamic. The increasing diversity has profound implications for many aspects of the pandemic, including viral pathogenicity, transmission, diagnosis, treatment, and vaccine development. HIV-1 genetic diversity surveillance is crucial in tackling the pandemic, but systematic surveillance at national, regional, and global levels has, to date, been lacking. Here, we discuss methods for gathering representative HI...

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Authors: Aldrich, C; Hemelaar, J

• Publication status: Published
• Journal: Trends in molecular medicine
• Volume: 18
• Issue: 12
• Pages: 691-694
• Publication date: 2012-12-01
• DOI: 10.1016/j.molmed.2012.06.004
• EISSN: 1471-499X
• ISSN: 1471-4914
• Language: English
• Keywords: Epidemiological Monitoring; Databases, Genetic; Molecular Epidemiology; HIV-1; World Health; Genetic Variation