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Hippocampal group III mGlu receptor mRNA levels are not altered in specific mouse models of stress, depression and antidepressant action.

Abstract:

The neurotransmitter glutamate is increasingly being implicated as playing a role in the molecular pathology underlying depression. The group III family of metabotropic glutamate (mGlu) receptors (mGlu(4,) mGlu(7) and mGlu(8) receptors) remains the most poorly investigated of all glutamate receptors in this regard, despite early research efforts showing that they may be major players in stress-induced pathology, genetic vulnerability to the onset of depression and in the action of pharmacothe...

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Publisher copy:
10.1016/j.pbb.2012.09.017

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Journal:
Pharmacology, biochemistry, and behavior
Volume:
103
Issue:
3
Pages:
561-567
Publication date:
2013-01-05
DOI:
EISSN:
1873-5177
ISSN:
0091-3057
URN:
uuid:874b7cbc-9c91-4165-80b5-9f5564745929
Source identifiers:
357971
Local pid:
pubs:357971

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