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A randomised trial of a contraceptive vaginal ring in women at risk of HIV infection in Rwanda: Safety of intermittent and continuous use

Abstract:

Contraceptive vaginal rings could play a role in expanding the contraceptive method mix and in preparing communities for the introduction of HIV prevention and multipurpose rings.We conducted an open label single-centre randomised clinical trial of intermittent versus continuous use of NuvaRing® in Kigali, Rwanda, in 2013-2014. We randomised 120 HIV-negative women 1:1 to intermittent use (three rings with a ring-free week in between rings) or continuous use (four rings without ring-free weeks...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1371/journal.pone.0197572

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
2 Division; NDM; Tropical Medicine; Vietnam / OUCRU
ORCID:
0000-0002-5728-0918
Van Nuil, JI More by this author
Uwineza, M More by this author
Umulisa, MM More by this author
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European and Developing Countries Clinical Trials Partnership (EDCTP) More from this funder
Publisher:
Public Library of Science Publisher's website
Journal:
PloS one Journal website
Volume:
13
Issue:
6
Pages:
e0197572
Publication date:
2018-06-01
DOI:
EISSN:
1932-6203
Pubs id:
pubs:856317
URN:
uri:8744d157-687a-4a20-80b0-4234ec96cc50
UUID:
uuid:8744d157-687a-4a20-80b0-4234ec96cc50
Local pid:
pubs:856317

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