- Abstract:
-
AIM: To determine the mechanism of weight loss caused by high doses of N-butyldeoxynojirimycin (NB-DNJ) in healthy lean and leptin-deficient obese (ob/ob) mice. METHODS: Healthy lean and obese mice were treated with NB-DNJ by the following methods: admixed with their diet, delivered by subcutaneously implanted mini-pumps or by intraperitoneal or intracerebroventricular (ICV) injection. Daily changes in body weight and food intake were recorded during the experimental period. The effect of NB...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1111/j.1463-1326.2006.00701.x
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- Journal:
- Diabetes, obesity and metabolism
- Volume:
- 10
- Issue:
- 2
- Pages:
- 159-166
- Publication date:
- 2008-02-05
- DOI:
- EISSN:
-
1463-1326
- ISSN:
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1462-8902
- URN:
-
uuid:873ac00f-8df6-40e5-af74-17477a19f0ab
- Source identifiers:
-
101075
- Local pid:
- pubs:101075
- Language:
- English
- Keywords:
- Copyright date:
- 2008
Journal article
N-butyldeoxynojirimycin causes weight loss as a result of appetite suppression in lean and obese mice.
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