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Research priorities in the management of severe Plasmodium falciparum malaria in children.

Abstract:

Severe malaria is a common reason for admission to paediatric wards in hospitals across sub-Saharan Africa. Despite over 100 years of research, mortality remains high. Deaths are associated with severe metabolic acidosis, shock, severe anaemia, hypoglycaemia, impaired consciousness, raised intracranial pressure, and status epilepticus. Most inpatient deaths occur within 24 h of admission to hospital, before the beneficial effects of treatment with antimalarial drugs are achieved. This review ...

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Publication status:
Published

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Publisher copy:
10.1179/136485906x91459

Authors


Newton, CR More by this author
Maitland, K More by this author
Journal:
Annals of tropical medicine and parasitology
Volume:
100
Issue:
2
Pages:
95-108
Publication date:
2006-03-05
DOI:
EISSN:
1364-8594
ISSN:
0003-4983
URN:
uuid:87214029-42e1-4874-84e6-b5a8d685d57c
Source identifiers:
185638
Local pid:
pubs:185638

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