Journal article icon

Journal article

Organ distribution of erythropoietin messenger RNA in normal and uremic rats.

Abstract:

We used RNAase protection assays to measure low levels of erythropoietin messenger RNA (EPO mRNA) in the organs of unstimulated rats, and to compare basal and stimulated levels of EPO mRNA in the kidneys and extrarenal organs of rats rendered uremic by subtotal nephrectomy, with pair-fed controls. Using this sensitive assay, EPO mRNA was measured in the kidneys of unstimulated control animals and was detectable, at lower levels, in the liver and lung. After exposure to hypoxia, there was a 15...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1038/ki.1991.181

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, CCMP, Biomedical Research Centre
Role:
Author
Journal:
Kidney international
Volume:
40
Issue:
1
Pages:
69-76
Publication date:
1991-07-05
DOI:
EISSN:
1523-1755
ISSN:
0085-2538
URN:
uuid:871e4d26-bdea-41f4-8286-c56561abb981
Source identifiers:
17067
Local pid:
pubs:17067

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP