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Autoregulation of convergent RNAi genes in fission yeast.

Abstract:

RNAi plays a central role in the regulation of eukaryotic genes. In Schizosaccharomyces pombe fission yeast, RNAi involves the formation of siRNA from dsRNA that acts to establish and maintain heterochromatin over centromeres, telomeres, and mating loci. We showed previously that transient heterochromatin also forms over S. pombe convergent genes (CGs). Remarkably, most RNAi genes are themselves convergent. We demonstrate here that transient heterochromatin formed by the RNAi pathway over RNA...

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Publication status:
Published

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Publisher copy:
10.1101/gad.618611

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Journal:
Genes and development
Volume:
25
Issue:
6
Pages:
556-568
Publication date:
2011-03-05
DOI:
EISSN:
1549-5477
ISSN:
0890-9369
URN:
uuid:870afe0b-d1bf-4458-afd5-1b63dc6bc962
Source identifiers:
120193
Local pid:
pubs:120193

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