- Abstract:
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BACKGROUND: CD8+ T cell responses play an important role in the control of HIV-1. The extensive sequence diversity of HIV-1 represents a critical hurdle to developing an effective HIV-1 vaccine, and it is likely that regional-specific vaccine strains will be required to overcome the diversity of the different HIV-1 clades distributed world-wide. Unfortunately, little is known about the CD8+ T cell responses against CRF01_AE, which is responsible for the majority of infections in Southeast As...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
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(pdf, 341.7KB)
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- Publisher copy:
- 10.1371/journal.pone.0023603
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- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PloS one Journal website
- Volume:
- 6
- Issue:
- 8
- Pages:
- Article: e23603
- Publication date:
- 2011-01-01
- DOI:
- EISSN:
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1932-6203
- ISSN:
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1932-6203
- URN:
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uuid:8701bae1-5865-44fd-ab41-4780625f48ab
- Source identifiers:
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175163
- Local pid:
- pubs:175163
- Copyright holder:
- Buranapraditkun et al.
- Copyright date:
- 2011
- Notes:
- Copyright 2011 Buranapraditkun et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Journal article
A novel immunodominant CD8+ T cell response restricted by a common HLA-C allele targets a conserved region of Gag HIV-1 clade CRF01_AE infected Thais.
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Funding
National Institutes of Health
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National Center for Genetic Engineering and Biotechnology (BIOTEC) Thailand
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Commission of Higher Education (CHE) in Thailand
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Royal Golden Jubilee Ph.D. Program
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Higher Education Research Promotion and National Research University Project of Thailand
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