Journal article
A novel immunodominant CD8+ T cell response restricted by a common HLA-C allele targets a conserved region of Gag HIV-1 clade CRF01_AE infected Thais.
- Abstract:
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BACKGROUND: CD8+ T cell responses play an important role in the control of HIV-1. The extensive sequence diversity of HIV-1 represents a critical hurdle to developing an effective HIV-1 vaccine, and it is likely that regional-specific vaccine strains will be required to overcome the diversity of the different HIV-1 clades distributed world-wide. Unfortunately, little is known about the CD8+ T cell responses against CRF01_AE, which is responsible for the majority of infections in Southeast As...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 341.7KB)
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- Publisher copy:
- 10.1371/journal.pone.0023603
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Authors
Funding
National Institutes of Health
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Ratchadaphiseksomphot Endowment Fund
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National Center for Genetic Engineering and Biotechnology (BIOTEC) Thailand
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Commission of Higher Education (CHE) in Thailand
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Royal Golden Jubilee Ph.D. Program
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Bibliographic Details
- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PloS one Journal website
- Volume:
- 6
- Issue:
- 8
- Article number:
- e23603
- Publication date:
- 2011-01-01
- DOI:
- EISSN:
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1932-6203
- ISSN:
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1932-6203
- Source identifiers:
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175163
Item Description
- Language:
- English
- Keywords:
- UUID:
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uuid:8701bae1-5865-44fd-ab41-4780625f48ab
- Local pid:
- pubs:175163
- Deposit date:
- 2012-12-19
Terms of use
- Copyright holder:
- Buranapraditkun et al
- Copyright date:
- 2011
- Notes:
- Copyright 2011 Buranapraditkun et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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