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A fine-scale chimpanzee genetic map from population sequencing.

Abstract:

To study the evolution of recombination rates in apes, we developed methodology to construct a fine-scale genetic map from high-throughput sequence data from 10 Western chimpanzees, Pan troglodytes verus. Compared to the human genetic map, broad-scale recombination rates tend to be conserved, but with exceptions, particularly in regions of chromosomal rearrangements and around the site of ancestral fusion in human chromosome 2. At fine scales, chimpanzee recombination is dominated by hotspots...

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Publisher copy:
10.1126/science.1216872

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Journal:
Science
Volume:
336
Issue:
6078
Pages:
193-198
Publication date:
2012-04-13
DOI:
EISSN:
1095-9203
ISSN:
0036-8075
URN:
uuid:8700f365-299c-4a68-be6f-d27457cc676a
Source identifiers:
316318
Local pid:
pubs:316318

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