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Energy based mechano-electrophysiological model of CNS damage at the tissue scale

Abstract:

Injuries to the central nervous system (CNS) have become a major health challenge in our society. Such injuries can affect the electrophysiological properties, and thus functional behaviour of the nervous system. Most of the related computational studies to date have mainly been focussed on the cellular, subcellular or axonal scales. Although essential for understanding the characteristics of spinal cord injury and traumatic brain injury at the cellular level, these approaches suffer from a l...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1016/j.jmps.2018.12.009

Authors


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ORCID:
0000-0003-4692-3508
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Institution:
University of Oxford
Division:
MPLS Division
Department:
Engineering Science
Oxford college:
St Hughs College
ORCID:
0000-0001-5026-8038
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Grant:
Seventh Framework Programme (FP7 2007–2013) ERC Grant Agreement No. 306587
Publisher:
Elsevier Publisher's website
Journal:
Journal of the Mechanics and Physics of Solids Journal website
Volume:
125
Pages:
22-37
Publication date:
2018-12-11
Acceptance date:
2018-12-10
DOI:
ISSN:
0022-5096
Pubs id:
pubs:952182
URN:
uri:86ff93d2-d7c0-4602-90c1-15c65274faa4
UUID:
uuid:86ff93d2-d7c0-4602-90c1-15c65274faa4
Local pid:
pubs:952182

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