Journal article
Natural history of GATA1 mutations in Down syndrome.
- Abstract:
-
Acquired mutations in megakaryocyte transcription factor GATA1 have recently been reported in Down syndrome (DS), transient myeloproliferative disorder (TMD), and acute megakaryoblastic leukemia (AMKL). To provide novel insight into GATA1 mutations in DS, genomic DNA was assayed from 12 AMKL and 4 TMD cases (including neonatal, prediagnosis samples in 4 of 16), neonatal blood spots from 21 DS children without clinically evident TMD or AMKL, and 62 non-DS cord blood samples, using techniques n...
Expand abstract
- Publication status:
- Published
Actions
Authors
Bibliographic Details
- Journal:
- Blood
- Volume:
- 103
- Issue:
- 7
- Pages:
- 2480-2489
- Publication date:
- 2004-04-01
- DOI:
- EISSN:
-
1528-0020
- ISSN:
-
0006-4971
- Source identifiers:
-
32570
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:32570
- UUID:
-
uuid:86f02d33-0030-46e1-a36c-c0ccc2140dca
- Local pid:
- pubs:32570
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2004
If you are the owner of this record, you can report an update to it here: Report update to this record