Natural history of GATA1 mutations in Down syndrome.

Ahmed, M; Sternberg, A; Hall, G; Thomas, A; Smith, O; O'Marcaigh, A; Wynn, R; Stevens, R; Addison, M; King, D; Stewart, B; Gibson, B; Roberts, I; Vyas, P

Abstract:

Acquired mutations in megakaryocyte transcription factor GATA1 have recently been reported in Down syndrome (DS), transient myeloproliferative disorder (TMD), and acute megakaryoblastic leukemia (AMKL). To provide novel insight into GATA1 mutations in DS, genomic DNA was assayed from 12 AMKL and 4 TMD cases (including neonatal, prediagnosis samples in 4 of 16), neonatal blood spots from 21 DS children without clinically evident TMD or AMKL, and 62 non-DS cord blood samples, using techniques n...

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APA Style

Ahmed, M., Sternberg, A., Hall, G., Thomas, A., Smith, O., O'Marcaigh, A., Wynn, R., Stevens, R., Addison, M., King, D., Stewart, B., Gibson, B., Roberts, I., & Vyas, P. (2004). Natural history of GATA1 mutations in Down syndrome. Blood, 103(7), 2480–2489.

MLA Style

Ahmed, M., et al. “Natural History of GATA1 Mutations in Down Syndrome.” Blood, vol. 103, no. 7, Blood, 2004, pp. 2480–89.

Chicago Style

Ahmed, M, A Sternberg, G Hall, A Thomas, O Smith, A O'Marcaigh, R Wynn, et al. 2004. “Natural History of GATA1 Mutations in Down Syndrome.” Blood 103 (7): 2480–89.
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