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Evidence for a dose effect of renin-angiotensin system inhibition on progression of microalbuminuria in Type 2 diabetes: a meta-analysis.

Abstract:

AIMS: Renin-angiotensin inhibitors in Type 2 diabetes and microalbuminuria reduce renal and cardiovascular risk, but evidence supporting use of maximal tolerated dose is unclear. We aimed to determine the extent of renin-angiotensin inhibitor dose-dependent effects from randomized trials carried out in a clinical setting. METHODS: In a meta-analysis of randomized clinical trials, alternate doses of angiotensin receptor blockers or angiotensin converting enzyme inhibitors in patients with Typ...

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Publication status:
Published

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Institution:
University of Oxford
Department:
National Institute for Health Research
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Institution:
University of Oxford
Department:
Oxford, MSD, Primary Care Health Sciences, PHC-Madox
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Institution:
University of Oxford
Department:
Oxford, MSD, Primary Care Health Sciences, PHC-Stats
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Institution:
University of Oxford
Department:
Oxford, MSD, Primary Care Health Sciences, PHC-Stats
More by this author
Institution:
University of Oxford
Department:
The Bodleian Health Care Libraries
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Journal:
Diabetic medicine : a journal of the British Diabetic Association
Volume:
28
Issue:
10
Pages:
1182-1187
Publication date:
2011-10-05
DOI:
EISSN:
1464-5491
ISSN:
0742-3071
URN:
uuid:86cefbd9-7db3-421d-8291-a9f83ca1a814
Source identifiers:
179983
Local pid:
pubs:179983

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