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A review of RCTs in four medical journals to assess the use of imputation to overcome missing data in quality of life outcomes.

Abstract:

BACKGROUND: Randomised controlled trials (RCTs) are perceived as the gold-standard method for evaluating healthcare interventions, and increasingly include quality of life (QoL) measures. The observed results are susceptible to bias if a substantial proportion of outcome data are missing. The review aimed to determine whether imputation was used to deal with missing QoL outcomes. METHODS: A random selection of 285 RCTs published during 2005/6 in the British Medical Journal, Lancet, New Englan...

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Publication status:
Published

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Publisher copy:
10.1186/1745-6215-9-51

Authors


Fielding, S More by this author
Maclennan, G More by this author
Ramsay, CR More by this author
Journal:
Trials
Volume:
9
Issue:
1
Pages:
51
Publication date:
2008
DOI:
EISSN:
1745-6215
ISSN:
1745-6215
URN:
uuid:86cbb141-8ddf-490c-ab64-961870d25e8e
Source identifiers:
449453
Local pid:
pubs:449453
Language:
English

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