Journal article
The p56lck SH2 domain mediates recruitment of CD8/p56lck to the activated T cell receptor/CD3/zeta complex.
- Abstract:
-
The CD4 or CD8 co-receptors and the T cell receptor (TCR) are though to interact with the same antigen-presenting major histocompatibility complex molecule in a stable ternary complex. Therefore, the TCR and its co-receptor need to come into close proximity on the surface of the T cell. We have previously shown that the interaction of the p56lck SH2 domain with zeta-associated, tyrosine phosphorylated ZAP-70 and Syk kinases leads to an enhanced association of CD4 with TCR/CD3/zeta complex aft...
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- Publication status:
- Published
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- Publisher copy:
- 10.1002/eji.1830260920
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Authors
Bibliographic Details
- Journal:
- European journal of immunology
- Volume:
- 26
- Issue:
- 9
- Pages:
- 2093-2100
- Publication date:
- 1996-09-01
- DOI:
- EISSN:
-
1521-4141
- ISSN:
-
0014-2980
- Source identifiers:
-
30113
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:30113
- UUID:
-
uuid:86c6dbdf-7679-40f7-b859-eea844fe23c0
- Local pid:
- pubs:30113
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 1996
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