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Genomic landscape of extended-spectrum β-lactamase resistance in Escherichia coli from an urban African setting

Abstract:

Efforts to treat Escherichia coli infections are increasingly being compromised by the rapid, global spread of antimicrobial resistance (AMR). Whilst AMR in E. coli has been extensively investigated in resource-rich settings, in sub-Saharan Africa molecular patterns of AMR are not well described. In this study, we have begun to explore the population structure and molecular determinants of AMR amongst E. coli isolates from Malawi.Ninety-four E. coli isolates from patients admitted to Queen's ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1093/jac/dkx058

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
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Grant:
PhD studentship to PM
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Grant:
Health Research Capacity Strengthening Initiative (HRCSI
Publisher:
Oxford University Press
Journal:
Journal of Antimicrobial Chemotherapy More from this journal
Volume:
72
Issue:
6
Pages:
1602-1609
Publication date:
2017-03-04
Acceptance date:
2017-02-01
DOI:
EISSN:
1460-2091
ISSN:
0305-7453
Pmid:
28333330

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