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Genomic landscape of extended-spectrum β-lactamase resistance in Escherichia coli from an urban African setting

Abstract:

Efforts to treat Escherichia coli infections are increasingly being compromised by the rapid, global spread of antimicrobial resistance (AMR). Whilst AMR in E. coli has been extensively investigated in resource-rich settings, in sub-Saharan Africa molecular patterns of AMR are not well described. In this study, we have begun to explore the population structure and molecular determinants of AMR amongst E. coli isolates from Malawi.Ninety-four E. coli isolates from patients admitted to Queen's ...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1093/jac/dkx058

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Tropical Medicine
Role:
Author
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Grant:
Health Research Capacity Strengthening Initiative (HRCSI)
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Grant:
PhD studentship to PM
Publisher:
Oxford University Press Publisher's website
Journal:
Journal of Antimicrobial Chemotherapy Journal website
Volume:
72
Issue:
6
Pages:
1602-1609
Publication date:
2017-03-04
Acceptance date:
2017-02-01
DOI:
EISSN:
1460-2091
ISSN:
0305-7453
Pubs id:
pubs:797858
URN:
uri:86975850-ae71-4bad-aaff-cbc4ce1c38a6
UUID:
uuid:86975850-ae71-4bad-aaff-cbc4ce1c38a6
Local pid:
pubs:797858
Paper number:
6

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