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Gene finding with a hidden Markov model of genome structure and evolution.

Abstract:

MOTIVATION: A growing number of genomes are sequenced. The differences in evolutionary pattern between functional regions can thus be observed genome-wide in a whole set of organisms. The diverse evolutionary pattern of different functional regions can be exploited in the process of genomic annotation. The modelling of evolution by the existing comparative gene finders leaves room for improvement. RESULTS: A probabilistic model of both genome structure and evolution is designed. This type of...

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Publication status:
Published

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Authors


Pedersen, JS More by this author
Journal:
Bioinformatics (Oxford, England)
Volume:
19
Issue:
2
Pages:
219-227
Publication date:
2003-01-05
DOI:
EISSN:
1367-4811
ISSN:
1367-4803
URN:
uuid:86890cb5-60fe-4800-8022-8052899faca3
Source identifiers:
102846
Local pid:
pubs:102846

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