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An empirical evaluation of guidelines on prostate-specific antigen velocity in prostate cancer detection.

Abstract:

BACKGROUND: The National Comprehensive Cancer Network and American Urological Association guidelines on early detection of prostate cancer recommend biopsy on the basis of high prostate-specific antigen (PSA) velocity, even in the absence of other indications such as an elevated PSA or a positive digital rectal exam (DRE). METHODS: To evaluate the current guideline, we compared the area under the curve of a multivariable model for prostate cancer including age, PSA, DRE, family history, and ...

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Publisher copy:
10.1093/jnci/djr028

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Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences
Role:
Author
Journal:
Journal of the National Cancer Institute
Volume:
103
Issue:
6
Pages:
462-469
Publication date:
2011-03-05
DOI:
EISSN:
1460-2105
ISSN:
0027-8874
URN:
uuid:86885891-e142-4b97-ada5-92587e49f56b
Source identifiers:
365878
Local pid:
pubs:365878

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