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Journal article

Bone marrow-derived stromal cells home to and remain in the infarcted rat heart but fail to improve function: an in vivo cine-MRI study.

Abstract:

Basic and clinical studies have shown that bone marrow cell therapy can improve cardiac function following infarction. In experimental animals, reported stem cell-mediated changes range from no measurable improvement to the complete restoration of function. In the clinic, however, the average improvement in left ventricular ejection fraction is around 2% to 3%. A possible explanation for the discrepancy between basic and clinical results is that few basic studies have used the magnetic resona...

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Publication status:
Published

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Publisher copy:
10.1152/ajpheart.00094.2008

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Role:
Author
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Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics, BHF Centre of Research Excellence
Role:
Author
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Journal:
American journal of physiology. Heart and circulatory physiology
Volume:
295
Issue:
2
Pages:
H533-H542
Publication date:
2008-08-05
DOI:
EISSN:
1522-1539
ISSN:
0363-6135
URN:
uuid:8683fd18-ceef-4a75-bf41-cfbfaa2dd2bb
Source identifiers:
105379
Local pid:
pubs:105379

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