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Correlation of [3H]diazepam binding density with anxiolytic locus in the amygdaloid complex of the rat.

Abstract:
Using [3H]diazepam binding, high concentrations of receptors were found in the frontal cortex and lateral amygdala. Infusions of chlordiazepoxide into the lateral amygdala induced a release of responding measured during the component of a conditioned emotional response task previously associated with an aversive stimulus. The lateral amygdala appears to be an important component of the forebrain circuitry involved in the expression of anxiety and sensitive to benzodiazepine drugs.
Publication status:
Published

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Authors


Thomas, SR More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Experimental Psychology
Journal:
Brain research
Volume:
342
Issue:
1
Pages:
85-90
Publication date:
1985-09-05
DOI:
EISSN:
1872-6240
ISSN:
0006-8993
URN:
uuid:866ae3db-410f-4774-b56f-c7d3c8baa51b
Source identifiers:
8473
Local pid:
pubs:8473

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