Book section
Determination of N-linked glycosylation in viral glycoproteins by negative ion mass spectrometry and ion mobility
- Abstract:
- Glycan analysis of virion-derived glycoproteins is challenging due to the difficulties in glycoprotein isolation and low sample abundance. Here, we describe how ion mobility mass spectrometry can be used to obtain spectra from virion samples. We also describe how negative ion fragmentation of glycans can be used to probe structural features of virion glycans.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Bibliographic Details
- Publisher:
- Springer New York Publisher's website
- Volume:
- 1331
- Pages:
- 93-121
- Series:
- Methods in Molecular Biology
- Host title:
- Carbohydrate-Based Vaccines
- Publication date:
- 2015-07-21
- DOI:
- EISSN:
-
1940-6029
- ISSN:
-
1064-3745
- Source identifiers:
-
531878
- ISBN:
- 9781493928736
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:531878
- UUID:
-
uuid:865ecae2-81c2-4083-8ec5-b4a05a0db1e6
- Local pid:
- pubs:531878
- Deposit date:
- 2016-04-22
Terms of use
- Copyright holder:
- Springer Science+Business Media New York
- Copyright date:
- 2015
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