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A meta-analysis using individual patient data of trials comparing artemether with quinine in the treatment of severe falciparum malaria.

Abstract:

We conducted a meta-analysis using individual patient data from randomized controlled trials comparing artemether and quinine in severe falciparum malaria. Eleven trials were identified, of which 8 were clearly randomized. Original individual patient data on 1919 patients were obtained from 7 trials, representing 85% of the patients in the original 11 studies. Overall there were 136 deaths among the 961 patients treated with artemether, compared with 164 in the 958 treated with quinine [14% v...

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Publication status:
Published

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Journal:
Transactions of the Royal Society of Tropical Medicine and Hygiene
Volume:
95
Issue:
6
Pages:
637-650
Publication date:
2001-01-01
DOI:
EISSN:
1878-3503
ISSN:
0035-9203
URN:
uuid:865bd9fd-b4ee-492f-a2ee-2867c4e35cd1
Source identifiers:
71265
Local pid:
pubs:71265

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