Journal article
Structure and function of the human MHC class Ib molecules HLA-E, HLA-F and HLA-G.
- Abstract:
-
The major histocompatibility (MHC) class Ib molecules HLA-E, HLA-F and HLA-G are relatively non-polymorphic compared to class Ia molecules. Both HLA-E and HLA-G bind peptides and are involved in natural killer (NK)-cell recognition, but the role of HLA-F is unclear. HLA-E binds specifically to the conserved leader sequence peptides from the class Ia MHC molecules and interacts on the cell surface with the CD94/NKG2 class of NK-cell receptors. The framework structure of HLA-E is similar to tha...
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- Publication status:
- Published
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Bibliographic Details
- Journal:
- Immunological reviews
- Volume:
- 163
- Issue:
- 1
- Pages:
- 129-138
- Publication date:
- 1998-06-01
- DOI:
- EISSN:
-
1600-065X
- ISSN:
-
0105-2896
- Source identifiers:
-
25024
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:25024
- UUID:
-
uuid:8659e8da-02ab-46b7-bb35-c838b0c3563d
- Local pid:
- pubs:25024
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 1998
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