Journal article
Cell mixing at a neural crest-mesoderm boundary and deficient ephrin-Eph signaling in the pathogenesis of craniosynostosis.
- Abstract:
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Boundaries between cellular compartments often serve as signaling interfaces during embryogenesis. The coronal suture is a major growth center of the skull vault and develops at a boundary between cells derived from neural crest and mesodermal origin, forming the frontal and parietal bones, respectively. Premature fusion of these bones, termed coronal synostosis, is a common human developmental anomaly. Known causes of coronal synostosis include haploinsufficiency of TWIST1 and a gain of func...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 2.4MB, Terms of use)
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- Publisher copy:
- 10.1093/hmg/ddl052
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Funding
Bibliographic Details
- Publisher:
- Oxford University Press
- Journal:
- Human molecular genetics More from this journal
- Volume:
- 15
- Issue:
- 8
- Pages:
- 1319-1328
- Publication date:
- 2006-04-01
- DOI:
- EISSN:
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1460-2083
- ISSN:
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0964-6906
Item Description
- Language:
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English
- Keywords:
-
- Pubs id:
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pubs:119727
- UUID:
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uuid:8657d0c7-7a14-4624-abee-6b6270195365
- Local pid:
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pubs:119727
- Source identifiers:
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119727
- Deposit date:
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2012-12-19
Terms of use
- Copyright holder:
- Merrill et al
- Copyright date:
- 2006
- Notes:
- Copyright © 2006 Merrill et al. Published by Oxford University Press. All rights reserved. The online version of this article has been published under an open access model. Users are entitled to use, reproduce, disseminate, or display the open access version of this article for non-commercial purposes provided that: the original authorship is properly and fully attributed; the Journal and Oxford University Press are attributed as the original place of publication with the correct citation details given; if an article is subsequently reproduced or disseminated not in its entirety but only in part or as a derivative work this must be clearly indicated. For commercial re-use, please contact: journals.permissions@oxfordjournals.org
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