Journal article
Functional consequences of the interaction of Ni2+ with the osteoclast Ca2+ 'receptor'.
- Abstract:
-
Ni2+ was used as an extracellular activator of the Ca2+ 'receptor' in order to study the regulation of osteoclast function in vitro. Application of different micromolar concentrations of Ni2+ to osteoclasts bathed in 1.25 mM [Ca2+] and 0.8 mM [Mg2+] caused a concentration-dependent elevation of cytosolic [Ca2+] measured in single cells using fura-2 fluorescence. Cytosolic [Ca2+] responses to 5 mM [Ni2+] showed a rapidly developing and use-dependent inactivation, unlike those induced by the ap...
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Bibliographic Details
- Journal:
- Experimental physiology
- Volume:
- 78
- Issue:
- 4
- Pages:
- 517-529
- Publication date:
- 1993-07-01
- EISSN:
-
1469-445X
- ISSN:
-
0958-0670
- Source identifiers:
-
475705
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:475705
- UUID:
-
uuid:86335638-f1c3-4976-a328-a07a517d7e59
- Local pid:
- pubs:475705
- Deposit date:
- 2014-07-14
Terms of use
- Copyright date:
- 1993
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