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Whole genome sequencing for M/XDR tuberculosis surveillance and for resistance testing

Abstract:

Whole genome sequencing (WGS) can help to relate Mycobacterium tuberculosis genomes to one another to assess genetic relatedness and infer the likelihood of transmission between cases. The same sequence data are now increasingly being used to predict drug resistance and susceptibility. Controlling the spread of tuberculosis and providing patients with the correct treatment are central to the World Health Organization's target to 'End TB' by 2035, for which the global prevalence of drug-resist...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.cmi.2016.10.014

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Clinical Laboratory Sciences
Role:
Author
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Publisher:
Elsevier Publisher's website
Journal:
Clinical Microbiology and Infection Journal website
Volume:
23
Issue:
3
Pages:
161-166
Publication date:
2016-10-24
Acceptance date:
2016-10-12
DOI:
EISSN:
1469-0691
ISSN:
1198-743X
Pmid:
27789378
Source identifiers:
656779
Language:
English
Keywords:
Pubs id:
pubs:656779
UUID:
uuid:862b786c-2587-406d-a75e-bdfa230e9f88
Local pid:
pubs:656779
Deposit date:
2017-04-29

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