Journal article
T cell recognition of hapten. Anatomy of T cell receptor binding of a H-2kd-associated photoreactive peptide derivative.
- Abstract:
-
To elucidate the structural basis of T cell recognition of hapten-modified antigenic peptides, we studied the interaction of the T1 T cell antigen receptor (TCR) with its ligand, the H-2Kd-bound Plasmodium berghei circumsporozoite peptide 252-260 (SYIPSAEKI) containing photoreactive 4-azidobenzoic acid (ABA) on P. berghei circumsporozoite Lys259. The photoaffinity-labeled TCR residue(s) were mapped as Tyr48 and/or Tyr50 of complementary determining region 2beta (CDR2beta). Other TCR-ligand co...
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- Publication status:
- Published
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- Publisher copy:
- 10.1074/jbc.274.6.3622
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Authors
Bibliographic Details
- Journal:
- Journal of biological chemistry
- Volume:
- 274
- Issue:
- 6
- Pages:
- 3622-3631
- Publication date:
- 1999-02-01
- DOI:
- EISSN:
-
1083-351X
- ISSN:
-
0021-9258
- Source identifiers:
-
17908
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:17908
- UUID:
-
uuid:8617bb9f-f72f-4150-93df-c84af15a8bea
- Local pid:
- pubs:17908
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 1999
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