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Journal article

Significant genetic heterogeneity of the SIVmac251 viral swarm derived from different sources.

Abstract:

Infecting rhesus macaques (Macaca mulatta) with the simian immunodeficiency virus (SIV) is an established animal model of human immunodeficiency virus (HIV) pathogenesis. Many studies have used various derivatives of the SIVmac251 viral swarm to investigate several aspects of the disease, including transmission, progression, response to vaccination, and SIV/HIV-associated neurological disorders. However, the lack of standardization of the infecting inoculum complicates comparative analyses. W...

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Publisher copy:
10.1089/aid.2011.0100

Authors


Strickland, SL More by this author
Lamers, SL More by this author
Huenink, E More by this author
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Journal:
AIDS research and human retroviruses
Volume:
27
Issue:
12
Pages:
1327-1332
Publication date:
2011-12-05
DOI:
EISSN:
1931-8405
ISSN:
0889-2229
URN:
uuid:85c650d7-2f67-4082-a96a-9098661f43cc
Source identifiers:
315467
Local pid:
pubs:315467

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